Where to eat between Gatlinburg and Myrtle Beach

This food trip itinerary gives you restaurant recommendations for places to eat over 4 days. Starting from Gatlinburg, you can leave at 7:00 am and drive for about 50 minutes to the first stop.

3360 Crabtree Rd
Waynesville, NC
(828) 627-3331
$
  118 reviews
Bakeries, Burgers, Steakhouses
6:30am to 9pm
Day 1. Arrive at 7:50 am. Eat for about 2½ hours. Then drive for about 10 minutes.
39 Miller St
Waynesville, NC
(828) 456-5559
$$
  414 reviews
American restaurants (New style)
11:30am to 9pm
Arrive at 10:30 am. Wait for about an hour. Double check the opening time of 11:30 am. Eat for about 2 hours. Then drive for about 40 minutes.
12 College St
Asheville, NC
(828) 255-4863
$$
Arrive at 2:10 pm. Eat for about 2 hours. Then drive for about 20 minutes.
100 Sierra Nevada Way
Mills River, NC
(828) 708-6242
$$
Arrive at 4:30 pm. Eat for about 2½ hours. Then drive for about 30 minutes.
16 Main St
Saluda, NC
(828) 749-1179
$$
Arrive at 7:30 pm. Eat for about 2 hours. Stay overnight. The next day, leave at 10:10 am. Then drive for about 50 minutes.
226 B W Main St
Spartanburg, SC
(864) 699-9669
$$
  462 reviews
Southern food
11am to 10pm
Day 2. Arrive at 11:00 am. Eat for about 2 hours. Then drive for about 10 minutes.
2550 Stone Station Rd
Roebuck, SC
(864) 587-1912
  3 reviews
Arrive at 1:10 pm. Eat for about an hour. Then drive for about 40 minutes.
910 S Broad St
Clinton, SC
(864) 833-0404
$
  79 reviews
Desserts, Pizza, Salad
11am to 9pm
Arrive at 3:00 pm. Eat for about 2 hours. Then drive for about 30 minutes.
1266 Wilson Rd
Newberry, SC
(803) 276-8885
$$
Arrive at 5:30 pm. Eat for about 2 hours. Then drive for about 30 minutes.
211 Chapin Rd
Chapin, SC
(803) 575-8470
$$
Arrive at 8:00 pm. Eat for about 2 hours. Stay overnight. The next day, leave at 7:00 am. Then drive for about 30 minutes.
819 Harden St
Columbia, SC
(803) 764-3512
$$
  728 reviews
Barbeque, Sandwiches
Day 3. Arrive at 7:30 am. Eat for about 2 hours. Then drive for about 10 minutes.
4927 Alpine Rd
Columbia, SC
(803) 788-8238
$
  319 reviews
Barbeque
11am to 8pm
Arrive at 9:50 am. Explore the area for about an hour. Double check the opening time of 11:00 am. Eat for about 2 hours. Then drive for about 30 minutes.
1011 Broad St
Camden, SC
(803) 425-4850
$$
  143 reviews
Mexican restaurants
11am to 10pm
Arrive at 1:30 pm. Eat for about 2 hours. Then drive for about an hour.
405 E Smith St
Timmonsville, SC
(843) 346-2381
Arrive at 4:30 pm. Eat for about 2 hours. Then drive for about 20 minutes.
1500 Second Loop Rd
Florence, SC
(843) 799-5579
$$
Arrive at 6:50 pm. Eat for about 2 hours. Stay overnight. The next day, leave at 11:00 am. Then drive for about 30 minutes.
419 Highway 38 W
Latta, SC
(843) 752-4700
$$
  169 reviews
Barbeque
11:30am to 8pm
Day 4. Arrive at 11:30 am. Eat for about 2 hours. Then drive for about 40 minutes.
725 S Main St
Aynor, SC
(843) 358-0207
  4 reviews
Coffee & Tea
6:30am to 8pm
Arrive at 2:10 pm. Eat for about an hour. Then drive for about 40 minutes.
740 Coastal Grand Cir
Myrtle Beach, SC
(843) 448-5533
$$
  569 reviews
Mexican restaurants
Arrive at 3:50 pm. Eat for about 2 hours. Then drive for about 10 minutes.

Reach your destination in Myrtle Beach around 6:00 pm after eating at 18 restaurants over 4 days. If you were to drive nonstop, it would take about 6½ hours driving roughly 376 miles straight to Myrtle Beach. Looking for more restaurants? You can choose a category below if you want to do an entire road trip full of Bakeries, Burgers, Steakhouses, American restaurants (New style), Breakfast & Brunch, Southern food, or more. Enjoy the journey!

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