Where to eat between Myrtle Beach and Gatlinburg

This food trip itinerary gives you restaurant recommendations for places to eat over 3 days. Starting from Myrtle Beach, you can leave at 3:00 pm and drive for about an hour to the first stop.

105 Harlee St
Marion, SC
(843) 702-7836
Day 1. Arrive at 4:00 pm. Eat for about 2 hours. Then drive for about 20 minutes.
5248 E Old Marion Hwy
Florence, SC
(843) 230-0953
$$
  60 reviews
Barbeque
10am to 8pm
Arrive at 6:20 pm. Eat for about 2 hours. Stay overnight. The next day, leave at 7:00 am. Then drive for about 20 minutes.
2701 David McLeod Blvd
Florence, SC
(843) 676-0355
$$$
  6 reviews
Pizza
Day 2. Arrive at 7:20 am. Eat for about 2 hours. Then drive for about 40 minutes.
117 Durant St
Bishopville, SC
(803) 484-6618
  4 reviews
American restaurants (Traditional)
8am to 3pm
Arrive at 10:00 am. Eat for about 2 hours. Then drive for about 30 minutes.
1011 Broad St
Camden, SC
(803) 425-4850
$$
  143 reviews
Mexican restaurants
11am to 10pm
Arrive at 12:30 pm. Eat for about 2 hours. Then drive for about 40 minutes.
7001 Parklane Rd
Columbia, SC
(803) 699-5422
$$
  440 reviews
Southern food, American restaurants (Traditional)
9:30am to 11pm
Arrive at 3:10 pm. Eat for about 2 hours. Then drive for about 10 minutes.
5200 Monticello Rd
Columbia, SC
(803) 735-1622
  6 reviews
Barbeque, Burgers
10am to 9pm
Arrive at 5:20 pm. Eat for about 2 hours. Then drive for about an hour.
2960 Hwy 56
Pauline, SC
(864) 586-1148
Arrive at 8:50 pm. Eat for about 2 hours. Stay overnight. The next day, leave at 9:40 am. Then drive for about 20 minutes.
930 E Main St
Spartanburg, SC
(864) 327-8228
$$
  343 reviews
Mexican restaurants
10am to 11pm
Day 3. Arrive at 10:00 am. Eat for about 2 hours. Then drive for about 20 minutes.
13241 Asheville Hwy
Inman, SC
(864) 708-1153
  8 reviews
Barbeque
6:30am to 10pm
Arrive at 12:20 pm. Eat for about 2 hours. Then drive for about an hour.
1939 Brevard Rd
Arden, NC
(828) 676-3175
$
  62 reviews
Mexican restaurants
11am to 8pm
Arrive at 3:20 pm. Eat for about 2 hours. Then drive for about 20 minutes.
12 College St
Asheville, NC
(828) 255-4863
$$
Arrive at 5:40 pm. Eat for about 2 hours. Then drive for about 20 minutes.

Asheville, NC
(828) 280-3156
  3 reviews
Barbeque
Arrive at 8:00 pm. Eat for about 2 hours. Then drive for about an hour.

Reach your destination in Gatlinburg around 11:00 pm after eating at 13 restaurants over 3 days. If you were to drive nonstop, it would take about 6½ hours driving roughly 377 miles straight to Gatlinburg. Looking for more restaurants? You can choose a category below if you want to do an entire road trip full of Southern food, American restaurants (Traditional), Barbeque, Pizza, Mexican restaurants, Burgers, or more. Enjoy the journey!

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